When working in a laboratory environment, personnel will encounter various hazards associated with the use of hazardous chemicals, equipment, or during certain processes. The Department of Environmental Health and Safety (EHS) has developed a University-wide Chemical Hygiene and Safety Plan (CHSP) and other supporting documents which provide general guidance for the recognition, evaluation, and control of these hazards. The CHSP is written in accordance with 29 CFR 1910.1450 (The Laboratory Standard), and with the National Research Council’s Prudent Practices in the Laboratory. The CHSP outlines minimum regulatory requirements and the most prudent practices for working safely in the laboratory environment. The CHSP does not adequately address the complete scope of hazards for all laboratory work; therefore, it is the responsibility of the Principal Investigators, or their designee to develop written standard operating procedures (SOPs) for specific operations.